U.S., Dec. 4 -- ClinicalTrials.gov registry received information related to the study (NCT07261930) titled 'Effectiveness of Tranexamic Acid in Reducing Blood Loss During Femoral Nail Surgery' on July 21.
Brief Summary: This clinical study aims to evaluate the safety and effectiveness of administering a single intravenous dose of tranexamic acid (TXA) before surgery to reduce blood loss in patients undergoing open intramedullary nailing for femoral shaft fractures. In many resource-limited settings, including Uganda, this surgical approach is common due to lack of fluoroscopic equipment, and it is known to be associated with significant perioperative blood loss.
Tranexamic acid is an antifibrinolytic agent that helps stabilize blood clots...