U.S., March 27 -- ClinicalTrials.gov registry received information related to the study (NCT06897059) titled 'Effectiveness of Smartphone Application for Adherence Support (Vuka+)' on March 20.

Brief Summary: This is a Type I Hybrid effectiveness-implementation trial to evaluate an HIV Pre-Exposure Prophylaxis (PrEP) medication adherence, persistence and social support app (Vuka+) for adolescent girls and young women (AGYW) in South Africa. This 6-month, 2-arm effectiveness and implementation trial (standard of care [SOC] vs. intervention app) will assess acceptability, feasibility and effectiveness. In addition, we will gather information on intervention delivery and barriers and facilitators for real-world delivery to inform future imple...