U.S., June 12 -- ClinicalTrials.gov registry received information related to the study (NCT07014397) titled 'Effect of Valaciclovir on Inter-Appointment Pain in Endodontic Treatment of Necrotic Teeth' on June 02.
Brief Summary: Aim: To investigate the effect of oral valacyclovir on inter-appointment endodontic pain in single-rooted necrotic teeth diagnosed with symptomatic apical periodontitis (SAP).
Materials and Methods: This study was a randomized, triple-blind, placebo-controlled clinical trial conducted on 38 teeth. Participants were assigned to intervention or control groups using stratified randomization based on gender and baseline pain severity. Both groups received similar root canal treatment; the only difference was the admini...