U.S., Sept. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07155746) titled 'Effect of Simulated Weight Loss on the Energy Cost of Locomotion in Overweight or Obese Adolescents' on Aug. 19.
Brief Summary: Current literature suggests that part of the energy response to weight loss is not due to changes in fat mass and lean mass, but rather to a homeostatic adaptation aimed at limiting or even preventing weight loss and preserving individuals' energy reserves, an adaptation known as "adaptive thermogenesis". This phenomenon calls for a closer look at the respective contributions of metabolic and mechanical changes induced by weight variations, with greater consideration given to the recently proposed hypothesi...