U.S., Feb. 22 -- ClinicalTrials.gov registry received information related to the study (NCT06840379) titled 'Effect of Sertraline on Inflammation in Hemodialysis Patients with Depression: a Randomized Controlled Trial' on Feb. 17.
Brief Summary: Depression is a common mental health condition among patients undergoing hemodialysis and is associated with a lower quality of life, poor treatment adherence, and worse overall health outcomes. Chronic inflammation, as measured by elevated C-reactive protein (CRP) levels, is frequently seen in these patients and contributes to an increased risk of cardiovascular disease, the leading cause of death in this population.
Sertraline, a widely used antidepressant, is effective in treating depression in...