U.S., May 22 -- ClinicalTrials.gov registry received information related to the study (NCT06982664) titled 'Effect of Preserving the Left Colic Artery on Proximal Bowel Perfusion' on April 16.
Brief Summary: Patients with rectal or rectosigmoid cancer undergoing radical resection will be randomly assigned to either high-tie (HT) or low-tie (LT) ligation of the Inferior Mesenteric Artery (IMA). Proximal bowel blood perfusion will be measured using Laser Speckle Contrast Imaging, and the perfusion characteristics will be compared between the two ligation groups.
Additionally, for participants randomized to the LT group, an embedded prospective cohort sub-study will be performed. This sub-study involves controlled, temporary intraoperative o...