U.S., Aug. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07134283) titled 'Effect of Preoperative Cold Therapy on Early Postoperative Outcomes in Total Knee Arthroplasty' on Aug. 08.
Brief Summary: This prospective, single-center, randomized controlled trial investigates the effects of preoperative cold therapy on early postoperative outcomes in patients undergoing unilateral primary total knee arthroplasty (TKA). A total of 208 patients were randomized into two groups: one receiving conventional cold therapy preoperatively and postoperatively, and the other receiving only routine postoperative cold therapy. Primary outcomes included postoperative pain (VAS), edema (thigh circumference), hemoglobin levels,...