U.S., April 30 -- ClinicalTrials.gov registry received information related to the study (NCT06948513) titled 'Effect of Over-the-counter Analgesics on Postoperative Pain' on April 21.
Brief Summary: In 2011, a randomized controlled trial compared acetaminophen, acetaminophen + ibuprofen, and acetaminophen + codeine for post-operative pain relief after Mohs surgery. In this study, the combination of acetaminophen + ibuprofen was shown to be superior to the other treatment groups at controlling postoperative pain. The study also detailed the timing at which patients experienced pain after cutaneous reconstruction, with peak pain scores occurring at 4 hours post-op for all three groups. Since its publication, the as needed dosage of acetamino...