U.S., April 10 -- ClinicalTrials.gov registry received information related to the study (NCT06919991) titled 'Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29)' on March 27.
Brief Summary: The purpose of the study is to assess the effects of multiple doses of itraconazole (a strong CYP3A4 inhibitor) on single dose PK of casdatifan in healthy adults and to assess the effects of multiple doses of phenytoin (a strong CYP3A4 inducer) on single dose PK of casdatifan in healthy adults.
Study Start Date: April, 2025
Study Type: INTERVENTIONAL
Condition:
Healthy Participants
Intervention:
DRUG: Casdatifan
Administered as a single dose in treatment Periods 1, 2, and 3
DRUG: Itraconazole
Administered as multip...