U.S., July 17 -- ClinicalTrials.gov registry received information related to the study (NCT07068568) titled 'Dose-Modulated Sonidegib Therapy for Periocular Basal Cell Carcinoma' on July 07.
Brief Summary: The goal of this clinical trial is to evaluate the safety, tolerability, and clinical outcomes of a dose-modulation strategy of Sonidegib in adult patients with locally advanced periocular basal cell carcinoma (laBCC) who are not candidates for surgery or radiotherapy. The main questions it aims to answer are:
* Can dose-adjusted Sonidegib treatment preserve ocular function and avoid disfiguring surgery in laBCC patients?
* What is the rate of tumor response, recurrence, and adverse events during dose-modulated treatment?
Researchers ...