U.S., March 4 -- ClinicalTrials.gov registry received information related to the study (NCT06854679) titled 'Dose Escalated Radiotherapy for Rectal Cancers Using MR-guided Radiotherapy' on Dec. 03, 2024.
Brief Summary: Standard radiotherapy in the UK involves having daily chemotherapy tablets with radiotherapy treatment for 5 weeks at a dose of 52.5Gy to the rectal cancer over 25 fractions. This is the likely treatment participants will be having if they decide not to take part in this study. Increasing the dose to 60Gy is shown to increase the chance that rectal cancer will be treated completely, a term known as "complete pathological response". Patients who have a complete pathological response after their treatment can avoid surgery and...