U.S., Dec. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07301788) titled 'Donor Circadian Rhythm and Its Correlation With Prognosis After Heart Transplantation' on Dec. 11.
Brief Summary: The goal of this observational study is to learn about the impact of donor heart procurement time based on circadian rhythm on the long-term outcomes of heart transplant recipients. The main question it aims to answer is:
Does the time of day when a donor heart is procured-specifically during the circadian repression phase (00:00-12:00) versus the activation phase (12:00-00:00)-affect post-transplant survival and rejection rates in patients with end-stage heart failure?
Patients undergoing heart transplantation at the ...