U.S., Jan. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07374705) titled 'Disentangling the Effect of Brain Insulin Resistance on Brain Health' on Jan. 20.
Brief Summary: People with diabetes are at increased risk of developing dementia, including Alzheimer's disease and vascular dementia. In addition, persons with diabetes have more pronounced age-related brain atrophy and cognitive difficulties compared to people without diabetes. The mechanisms behind the effects on the brain of diabetes are still unclear. New research suggests that the brains of some people with diabetes do not respond normally to insulin signals, a condition known as brain insulin resistance (BIR). To date, there have been no large c...