Clinical Trial: Direct Carotid Sinus Nerve Stimulation in Anesthetized Human Subjects

U.S., May 15 -- ClinicalTrials.gov registry received information related to the study (NCT06969846) titled 'Direct Carotid Sinus Nerve Stimulation in Anesthetized Human Subjects' on April 04.

Brief Summary: Uncontrolled hypertension (HTN) is growing in incidence globally creating a critical need for alternative therapeutic strategies. Directly stimulating the carotid sinus nerve (CSN) is known to potentially reduce blood pressure (BP) but its clinical efficacy has not been consistently demonstrated with existing electrode technologies in humans.

We investigated the effect of acute direct CSN stimulation on BP and HR in anesthetized humans using an application-specific multi-contact electrode.

Study Start Date: April 03, 2020

Study Type:...