U.S., Jan. 15 -- ClinicalTrials.gov registry received information related to the study (NCT07341334) titled 'Digital Speech Markers for Monitoring ALS in Spanish Speakers' on Dec. 05, 2025.
Brief Summary: The goal of this observational study is to learn how speech and breathing change over time in Spanish-speaking individuals with amyotrophic lateral sclerosis (ALS) compared to age- and gender-matched individuals without ALS.
The main questions it aims to answer are:
Can speech and breathing measures collected through a smartphone application serve as reliable digital biomarkers to track bulbar disease decline in Spanish-speaking people with ALS?
How do these measures differ between individuals with ALS and those without ALS?
Researche...