U.S., Nov. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07241351) titled 'Dexmedetomidine as an Adjunct to Fentanyl for Term Neonates on Mechanical Ventilation' on Nov. 17.
Brief Summary: Despite well conducted studies on pain management in mechanically ventilated neonates, there is still a need for exploration of appropriate and accurate pharmacological management strategies for this ongoing pain, and assessment of the clinical impact of the used drugs for analgesia and sedation. Opioids, such as fentanyl, are frequently used for analgesia and sedation in mechanically ventilated neonates with their short- and long-term adverse consequences Dexmedetomidine (DEX) is a specific alpha2 adrenergic agonist wit...