U.S., July 25 -- ClinicalTrials.gov registry received information related to the study (NCT07084675) titled 'Dehydration, Rehydration, and Impact on Physiology' on July 03.
Brief Summary: Our goal is to determine whether hydration status influences inflammation, and overall physiological performance in adults aged 45-65.
Aim 1: The effects of 4-day mild dehydration followed by 4-day rehydration (defined as approximately 2-3% body mass loss) on H2O2, upstream inflammatory signal (NFkB), mitochondrial fragmentation, and autophagy in circulating PBMCs.
Aim 2: The effects of 4-day mild dehydration followed by 4-day rehydration (defined as approximately 2-3% body mass loss) on fasting glucose, sleep performance, and strength performance.
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