U.S., April 8 -- ClinicalTrials.gov registry received information related to the study (NCT06915038) titled 'ctHPVDNA in HPV Positive Squamous Cell Carcinoma of the Oropharynx' on April 01.
Brief Summary: This study is a prospective phase II trial, designed to assess the efficacy and feasibility of adjuvant treatment deintensification guided by ctHPVDNA levels for patients with HPV+OPSCC who undergo transoral surgery and neck dissection.
Study Start Date: May, 2025
Study Type: INTERVENTIONAL
Condition:
Squamous Cell Carcinoma of Oropharynx
HPV Positive Cancer
Throat Cancer
Tonsil Cancer
Intervention:
RADIATION: Adjuvant Radiation 30 Gray
If undetectable postoperative ctHPVDNA levels and five or more positive nodes, or confirmed extr...