U.S., Feb. 20 -- ClinicalTrials.gov registry received information related to the study (NCT06835088) titled 'Cryopreservation of Ovarian Tissue: Reimplantation Rate and Effects on Ovarian Function' on Nov. 28, 2024.
Brief Summary: Premature ovarian failure (POI) is a clinical syndrome defined by the loss of ovarian activity before age 40. POI is characterized by amenorrhea or oligomenorrhea with elevated gonadotropins, low estradiol and serious consequences on fertility.
The prevalence of POI in the general population is about 1%. In recent years, the incidence of iatrogenic POI in cancer women is increasing: 4% of patients of fertile age are diagnosed with neoplasms and gonadal treatments that can sterilize them, such as chemotherapy and...