U.S., Feb. 15 -- ClinicalTrials.gov registry received information related to the study (NCT06828822) titled 'CongenItal Naevus Cohort for Longitudinal Evaluation' on Jan. 29.
Brief Summary: Congenital Nevus (CN) is a pigmented skin lesion present at birth, which grows in size as the child grows. It can vary in appearance and is classified by its size, from small (less than 1.5 cm) to giant (greater than 40 cm). CN is associated with genetic mutations, mainly in the NRAS/BRAF genes.
A large CN can lead to several clinical issues, including:
Risk of neurological disorders: Large CN can be associated with neurological abnormalities such as neuro-meningeal melanosis, hydrocephalus, or brain malformations. These conditions may cause early neu...