U.S., Jan. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07365956) titled 'Comparison of Oral Care Solutions on Oral Microbial Colonization in Neurosurgical ICU Patients' on Dec. 23, 2025.
Brief Summary: In the high-stakes environment of the Neurosurgery Intensive Care Unit (NSICU), patient stability extends beyond neurological monitors and intracranial pressure readings. A critical yet often underemphasized front line of defense is oral health. Neurosurgery patients, frequently intubated, on mechanical ventilation, or with depressed consciousness, are at extreme risk for Ventilator-Associated Pneumonia (VAP) and systemic infections. Pathogenic oral microbiota can be aspirated into the lower respiratory tr...