U.S., Dec. 31 -- ClinicalTrials.gov registry received information related to the study (NCT07310524) titled 'COMPARISON OF OPIOID-FREE AND OPIOID-BASED ANESTHESIA TECHNIQUES ON qNOX INDEX IN ABDOMINAL SURGERY UNDER GENERAL ANESTHESIA' on Dec. 01.
Brief Summary: This study is a randomized, double-blind controlled clinical trial designed to evaluate the effects of opioid-free anesthesia (OFA) compared with opioid-based anesthesia (OBA) in adult patients undergoing elective abdominal surgery under general anesthesia. Opioid-free anesthesia uses a multimodal combination of ketamine, lidocaine, and dexmedetomidine to provide analgesia and autonomic stability without intraoperative opioid administration. In contrast, the opioid-based approach ut...