U.S., Dec. 17 -- ClinicalTrials.gov registry received information related to the study (NCT07285980) titled 'Comparison of Bier Block and Lidocaine-Propofol Mixture for Prevention of Propofol Injection Pain' on Nov. 20.
Brief Summary: The goal of this clinical trial was to evaluate methods to prevent pain on intravenous administration of propofol during induction of anesthesia. Propofol frequently causes a burning or painful sensation when injected into a peripheral vein.
This randomized study compared three approaches in adult patients scheduled for elective surgery: propofol alone (control), propofol with 40 mg lidocaine mixed directly, and a brief intravenous lidocaine under venous occlusion (Bier block) using 40 mg for 2 minutes befor...