Clinical Trial: COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"

U.S., Dec. 16 -- ClinicalTrials.gov registry received information related to the study (NCT07281027) titled 'COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"' on Nov. 21.

Brief Summary: The goal of this clinical trial is to find out whether two existing medications-anakinra and tocilizumab-can effectively treat a rare and life-threatening brain condition called NORSE (New-Onset Refractory Status Epilepticus). NORSE causes continuous seizures in previously healthy children and adults and does not respond to standard treatments. It often leads to long-term disability or death.

Doctors currently use anakinra and tocilizumab as second-line treatments when first-line therapies fail, but there is no clear evidence showing w...