U.S., Feb. 4 -- ClinicalTrials.gov registry received information related to the study (NCT07384624) titled 'Combining Latency Reversing Agents to Address the HIV Reservoir' on Jan. 08.
Brief Summary: The PLUTO trial aims to contribute to the worldwide search for a functional cure of HIV. One the strategies ("shock and kill' strategy) aims to reverse the HIV-reservoir from latency by increasing cell-associated HIV-RNA, which will lead to increased antigen presentation, trigger immune recognition, and facilitate the elimination of reservoir cells. Participants of the trial are adults with HIV with undetectable viral load that are able to give informed consent to participate in the trial, in total 30 patients will be recruited. The investigat...