U.S., Oct. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07201311) titled 'Combined Gastrointestinal Decontamination in Acute Severe Poisoning' on Sept. 09.
Brief Summary: Gastrointestinal absorption of high dose medication (toxicant) ingested under solid form for suicidal purposes, is prolonged in patients who need intensive care admission and mechanical ventilation. This is due to the large ingested amounts, slowed blood circulation in the digestive system due to low blood pressure, and the formation of conglomerates of pills (pharmacobezoars).
We make the hypothesis that combined decontamination of the digestive system with activated charcoal plus polyethylene glycol may reduce absorption of the ingeste...