U.S., March 11 -- ClinicalTrials.gov registry received information related to the study (NCT06865924) titled 'Colangioids to Define the Genetic Factors Involved in Atypical Primary Sclerosing Cholangitis' on Feb. 19.
Brief Summary: Primary sclerosing cholangitis (PSC) is a rare, progressive and often fatal disease of the intrahepatic or extrahepatic bile ducts, with an estimated prevalence in Western countries of 1/10,000. Biliary disease in PSC is represented by cholestasis, chronic inflammation of the bile ducts, the small tubes through which bile passes, progressive concentric fibrosis around the bile ducts2. This results in an obstruction to the passage of bile, which can lead to the development of cirrhosis with complications related ...