U.S., Feb. 7 -- ClinicalTrials.gov registry received information related to the study (NCT06812715) titled 'Clonal Dynamics of Chronic Lymphocytic Leukaemia Treated with Pirtobrutinib After Previous Treatment with Zanubrutinib' on Feb. 02.
Brief Summary: This is a multicentre single-arm prospective phase II trial evaluating pirtobrutinib in the treatment of relapsed/refractory (R/R) Chronic Lymphocytic Leukaemia (CLL) patients who have previously received zanubrutinib, and to specifically evaluate Bruton Tyrosine Kinase (BTK) mutational status (clonal dynamics) before, during and after treatment with pirtobrutinib.
Study Start Date: May, 2025
Study Type: INTERVENTIONAL
Condition:
Chronic Lymphocytic Leukemia
Intervention:
DRUG: Pirto...