U.S., Sept. 4 -- ClinicalTrials.gov registry received information related to the study (NCT07152223) titled 'Clinical Study on the Safety and Efficacy of CD19-BCMA CAR-T Cell Therapy for Connective Tissue Diseases' on Aug. 26.
Brief Summary: This study is a single-arm, single-center Investigator-Initiated Trial (IIT) designed to evaluate the safety, pharmacokinetic profile, and preliminary efficacy of CD19-BCMA CAR-T cells in subjects diagnosed with connective tissue diseases.
Study Start Date: Aug. 30
Study Type: INTERVENTIONAL
Condition:
Connective Tissue Diseases
Intervention:
BIOLOGICAL: CAR-T
Eligible subjects who successfully passed screening will receive CAR-T cell infusion on Day 0 after lymphodepleting preconditioning chemo...