U.S., Sept. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07184450) titled 'Clinical Study of BCMA/CD70-targeted CAR-T Therapy for Refractory Pediatric Rheumatic Diseases' on Sept. 05.
Brief Summary: This is an investigator-initiated trial to evaluate the efficacy and safety of BCMA/CD70-targeted CAR-T in the treatment of refractory pediatric rheumatic diseases.
Study Start Date: Sept. 01
Study Type: INTERVENTIONAL
Condition:
Juvenile Dermatomyositis (JDM)
Polyarticular Juvenile Idiopathic Arthritis
Systemic Sclerosis (SSc)
Primary Sjogren's Syndrome
Intervention:
BIOLOGICAL: BCMA/CD70-targetd CAR-T
Subjects underwent lymphocytetion cheotherapy and then received a single intravenous cell infusio...