U.S., Feb. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07387796) titled 'Clinical and Neurobehavioral Changes With Weight Loss Drug Discontinuation and Reinitiation' on Jan. 08.
Brief Summary: The goal of this clinical study with research procedures is to learn how stopping and restarting tirzepatide (a medication that helps regulate blood sugar and appetite) affects brain activity, behavior, and health in adults ages 18-70 who are currently taking tirzepatide. Specifically, the study aims to examine how a short pause in tirzepatide affects hunger, mood, sleep, and daily functioning; how stopping and restarting tirzepatide alters brain chemistry and brain responses to food-related images; and how these ch...