U.S., Nov. 15 -- ClinicalTrials.gov registry received information related to the study (NCT07228338) titled 'Cholinergic Enhancement of Theta' on Nov. 12.
Brief Summary: The goal of this study is to learn about the effects of Cobenfy KarXT (xanomeline and trospium chloride) on episodic memory processing, including specific effects on areas of the brain involved in memory and changes it may have on brain activity. The investigators will do this by testing epileptic patients who are already undergoing intracranial surgery for seizure monitoring, and measuring the activity from the brain areas being assessed.
The main questions it aims to answer are 1) whether Cobenfy KarXT changes memory activity based on its agonist effect on muscarinic re...