Clinical Trial: Chemotherapy With Rituximab for Aggressive B-NHL in Children and Adolescents

U.S., Sept. 12 -- ClinicalTrials.gov registry received information related to the study (NCT07168980) titled 'Chemotherapy With Rituximab for Aggressive B-NHL in Children and Adolescents' on Sept. 04.

Brief Summary: The purpose of this study is to test whether intensive chemotherapy combined with early, adequate, and intensive use of Rituximab for aggressive B-NHL in children and adolescents can improve the EFS and OS compared with the historical study CCCG-BNHL-2015.

Study Start Date: July 01

Study Type: INTERVENTIONAL

Condition: Mature B-cell Non-Hodgkin Lymphoma

Intervention: DRUG: Cyclophosphamide, Vincristine, Cytarabine, Doxorubincin, Prednisone

Cyclophosphamide 800mg/m2, D1, then 200mg/m2, D2~4;Vincristine 1.5mg/m2 (MAX 2mg),...