Clinical Trial: ChatGPT-5 vs. CDSS for Drug-Drug Interactions in ICU

U.S., Jan. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07314125) titled 'ChatGPT-5 vs. CDSS for Drug-Drug Interactions in ICU' on Dec. 10, 2025.

Brief Summary: Evaluating ChatGPT-5 for Detecting Potential Drug-Drug Interactions in Intensive Care: A Comparative Analysis with a Clinical Decision Support System

Background:

Polypharmacy is a frequent challenge in intensive care units (ICUs), where critically ill patients are exposed to multiple concurrent medications. This situation significantly increases the risk of potential drug-drug interactions (pDDIs), which may contribute to adverse drug events, prolonged ICU stays, and higher morbidity and mortality rates. Ensuring timely and accurate detection of ...