U.S., Jan. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07357090) titled 'Carbon Dioxide Administration and Brain Waste Clearance' on Jan. 09.
Brief Summary: The current study tests whether different exposures to carbon dioxide (CO2) can safely result in the increased movement of proteins from the brain into the blood. The investigators believe that this would be a proxy for the brain clearing waste products more effectively. The current study will use a counter-balanced design, in which individuals with and without a history of traumatic brain injury (TBI) will receive different levels of CO2 (targeted changes of approximately 5 or 10 mmHG in end-tidal CO2) approximately one week apart. The counter-balan...