U.S., Nov. 29 -- ClinicalTrials.gov registry received information related to the study (NCT07253051) titled 'BRCA Mutation Carriers' Platform a Multicenter Study' on Nov. 19.
Brief Summary: Subjects who carry mutations in breast cancer susceptibility genes 1 and 2 (BRCA1 and BRCA2 genes) are at higher risk of developing cancers. Despite the cumulative amount of evidence published in the literature in the last two decades, the management of BRCA mutation carriers is still not completely defined.
Since the prevalence of the mutation is estimated to be 1:400 - 1:500 individuals, the total number of BRCA mutation carriers should be around 140.000 - 150.000 in the Italian population. It is estimated that 87% of women with BRCA mutations will e...