U.S., March 20 -- ClinicalTrials.gov registry received information related to the study (NCT06883461) titled 'Association Between Age-related Macular Degeneration and Cognitive Impairment Based on Exosome Proteomics' on March 13.
Brief Summary: Aim: Preliminary serum exosomal proteomics of patients with dry age-related macular degeneration (AMD) and mild cognitive impairment (MCI) were analyzed using proteomics technology.
Methods: Peripheral serum samples were collected from patients with AMD, MCI, comorbid conditions, and the control group. Exosomes were isolated from these samples and analyzed using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Differentially expressed proteins (DEPs) associated with the two diseases were ...