U.S., Sept. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07154615) titled 'Assessing Immune Dysfunction in Sepsis' on Aug. 26.
Brief Summary: Sepsis leads to sustained immune system dysfunction resulting in increased susceptibility to secondary infection while in the hospital or after discharge. Consequently, many of the ~2 million Americans that develop sepsis every year will end up back in the ICU, weeks and months later. The objective of this study is to define the cellular and molecular mechanisms driving the dysfunction and reprogramming of T cells and B cells that mediate cellular and humoral immunity using a combination of phenotypic, functional, genomic, and metabolomic assays.
Study Start Date: O...