U.S., June 25 -- ClinicalTrials.gov registry received information related to the study (NCT07034430) titled 'Aortic Dilatation Under 5 cm: Genetic Risk Mapping' on June 14.
Brief Summary: This retrospective study investigates the prevalence of genetic mutations in patients with ascending aortic dilatation measuring between 4.0 and 5.0 cm-below the standard surgical threshold. Using Next Generation Sequencing (NGS), both syndromic and non-syndromic aortopathy gene panels were analyzed in 102 patients who had no history of aortic surgery, dissection, or known genetic disorders. Findings will be compared with population data to better understand genetic risk profiles in borderline aortic dilatation, potentially supporting earlier intervention...