U.S., Dec. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07256561) titled 'Antimicrobial and Anti-inflammatory Effects of Simvastatin as an Intracanal Medication' on Nov. 20.
Brief Summary: Successful endodontic treatment and a predictable outcome can only be achieved by effective root canal debridement, irrigation, and elimination of microorganisms .
The outcome of endodontic treatment performed in controlled clinical environment has demonstrated success rate around 90%.
In certain cases, endodontic treatment may fail, one of the most common reasons is inability to eliminate microorganisms from the root canal. When non-surgical root canal therapy fails, the treatment options include orthograde re-treatme...