U.S., April 17 -- ClinicalTrials.gov registry received information related to the study (NCT06930911) titled 'Antibiotic Stewardship to Prevent Early Sepsis in Preterm Infants' on April 09.
Brief Summary: Early onset sepsis (EOS) occurs in newborns within the first 72 hours of life, and is rare, about 0.8 cases per 1000 births (1). It is more frequent in premature infants and potentially more severe (as much as 75% of deaths has been reported in extreme premature infants (1)). Infection is considered as confirmed when blood or cerebral fluid cultures detect a pathogen (1). It is considered probable when cultures are negative, but there are clinical (fever, hemodynamic failure, severe respiratory condition) and biological (inflammatory mark...