U.S., Jan. 15 -- ClinicalTrials.gov registry received information related to the study (NCT07340008) titled 'Analgosedation With Ketamine, Nalbuphine, or Dexmedetomidine for Suture Removal in Children After Cleft Surgery' on Aug. 27, 2025.
Brief Summary: This prospective, randomized study is designed to compare the efficacy and safety of three sedative-analgesic agents-intramuscular ketamine, intranasal nalbuphine, and intranasal dexmedetomidine-for procedural sedation in children undergoing suture removal following cleft palate, alveolar ridge, or lip surgery. The study will include 60 children aged 6 months to 3 years, randomly assigned to one of three intervention groups.
The primary objectives are to compare time to achieve adequate s...