U.S., Sept. 9 -- ClinicalTrials.gov registry received information related to the study (NCT07159607) titled 'Amino Acid PET-based Response Assessment in IDH-mutant Gliomas (APPEAR)' on Aug. 21.
Brief Summary: Background: The radiological follow-up of diffuse gliomas is challenged by the difficult distinction of true progression from treatment-related changes. To this end, the Response Assessment in Neuro-Oncology (RANO) Working Group has issued specific recommendation for the standardized evaluation of magnetic resonance imaging (MRI). In addition, positron emission tomography (PET) using radiolabeled amino acids allows for the delineation of metabolically active tumor regions in brain tumors, and guidelines for PET-based response assessme...