U.S., June 14 -- ClinicalTrials.gov registry received information related to the study (NCT07018934) titled 'Alfuzosin and Mirabegron for Double-J Stent Symptoms' on May 26.
Brief Summary: This prospective randomized controlled trial investigates the effects of alfuzosin, mirabegron, and their combination on stent-related symptoms and outcomes in patients undergoing DJ stent placement after retrograde intrarenal surgery (RIRS) for renal stones. The primary outcomes include stone-free rate and residual fragment status, while secondary outcomes focus on stent-related pain and lower urinary tract symptoms (LUTS). Patients will be randomly assigned to one of four groups: alfuzosin only, mirabegron only, combination therapy, or control. Pain an...