U.S., March 11 -- ClinicalTrials.gov registry received information related to the study (NCT06865521) titled 'Akkermansia Probiotics Plus Anti-PD-1 Monoclonal Antibody in MSS/pMMR Advanced Colorectal Cancer' on Feb. 21.
Brief Summary: The investigators propose to conduct a single-center, single-arm, Phase I clinical study to explore the safety and efficacy of Akkermansia probiotics combined with anti-PD-1 monoclonal antibody in patients with MSS/pMMR advanced colorectal cancer, as well as its impact on gut microbiota and the immune microenvironment.
Study Start Date: Feb. 21
Study Type: INTERVENTIONAL
Condition:
Colo-rectal Cancer
PD-1 Inhibitor
Akkermansia Muciniphila
Intervention:
DIETARY_SUPPLEMENT: Akkermansia Probiotics
After e...