U.S., July 2 -- ClinicalTrials.gov registry received information related to the study (NCT07046429) titled 'Affect of Melatonin on Sleep and Cognition in Cirrhosis' on June 23.
Brief Summary: The goal of this clinical trial is to learn the affect of melatonin on sleep, cognitive function, and quality of life (QoL) in patients with cirrhosis and a complication called hepatic encephalopathy (HE). The main questions this study aims to answer are:
* Does taking melatonin increase REM sleep, an important part of healthy sleep that is reduced in cirrhosis?
* Does taking melatonin improve cognitive function and reported QoL?
This is a pilot study, where participants will:
* take one month of melatonin, followed by one month of thiamine, which...