U.S., Oct. 4 -- ClinicalTrials.gov registry received information related to the study (NCT07205757) titled 'Adding Lidocaine to Custodiol Mixture' on Sept. 18.
Brief Summary: The Bretschneider solution, also known as Custodiol, has been widely used in open-heart surgery requiring cardiopulmonary bypass (CPB) since its introduction in 1970. Custodiol is widely favored by cardiac surgeons, being administered as a single dose, and is supposed to offer myocardial protection for up to three hours, permitting an uninterrupted surgical time, especially for intricate procedures The literature continues to debate the superiority of custodial and other cardioplegic solutions, such as the Del Nido and St. Thomas solutions, regarding both short-term a...