U.S., April 4 -- ClinicalTrials.gov registry received information related to the study (NCT06909045) titled 'Adaptive vs. Continuous Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease' on March 10.
Brief Summary: The objective of the CLOSE-PD study is to compare the efficacy of adaptive deep brain stimulation (aDBS) with continue deep brain stimulation (cDBS) in patients with Parkinson's disease. The main question it aims to answer is:
- whether the change in daily mean ON time without troublesome dyskinesia in aDBS is greater than cDBS over a six-month follow-up period?
Researchers will compare aDBS to regular continue deep brain stimulation (cDBS).
Participants will:
* be randomized 1:1 to aDBS or cDBS;
* follow-up wi...