U.S., May 9 -- ClinicalTrials.gov registry received information related to the study (NCT06962501) titled 'Acute Oral Ketone Monoester Supplementation and Resting-state Brain Connectivity' on April 09.
Brief Summary: The primary objectives of this pilot study are to test if a single dose of an oral ketone monoester supplement will increase blood flow and connectivity in the brain in adults with subjective cognitive decline (SCD) or mild cognitive impairment (MCI).
The main questions it aims to answer are:
Does a single dose of an oral ketone supplement increase global cerebral blood flow (CBF)?
Does a single dose of an oral ketone supplement improve resting-state functional connectivity in the Default Mode Network (DMN)?
Does the incre...