Clinical Trial: Acid-suppression Drugs After Prophylactic Endoscopic Variceal Treatment of Esophagogastric Variceal Bleeding in Cirrhosis

U.S., Nov. 26 -- ClinicalTrials.gov registry received information related to the study (NCT07248722) titled 'Acid-suppression Drugs After Prophylactic Endoscopic Variceal Treatment of Esophagogastric Variceal Bleeding in Cirrhosis' on Nov. 18.

Brief Summary: Traditionally, it is considered that gastric acid delays ulcer healing, and acid suppression can reduce the risk of post-banding ulcer bleeding and promote mucosal healing at the ulcer site. A systematic review and meta-analysis performed by our team demonstrated that acid suppression significantly reduced the incidence of bleeding following prophylactic endoscopic variceal treatment (EVT), but had no significant effect on the incidence of mortality, adverse events, or length of stay. ...